INFLUENCE OF PATHOLOGIC
METEOSENSITIVITY ON DEVELOPMENT OF ARTERIAL HYPERTENSION IN THE NORTH

Khasnulin Vyacheslav Ivanovich, Doctor of medical sciences, professor, head of adaptation mechanisms laboratory, Research Center of Clinical and Experimental Medicine, Sibirian unit of the Russian Academy of Medical Sciences (Novosibirsk, 2 Ti-makova str.), hasnulin@ngs.ru
Sevost'yanova Evgeniya Viktorovna, Candidate of medical sciences, senior staff scientist, Research Center of Clinical and Experimental Medicine, Sibirian unit of the Russian Academy of Medical Sciences (Novosibirsk, 2 Timakova str.), luck.nsk@rambler.ru

613.1, 616.092, 616.1

To study the effect of pathological meteosensitivity on progression of arterial hypertension (AH) in patients with AH, the inhabitants of the North. The study included 196 patients with AH I-II stage (aged 20–64 years, mean age –43,9 ± 0,5 years), the inhabitants of the North of RF. A comprehensive clinical and laboratory, electrocardiographic and biochemical examination, assessment of severity of clinical manifestations of the disease and the level of pathological meteosensitivity using the computer program "SKREENMED" (state reg. N 970035 from 29.01.1997) was car-ried out. With the growth of pathological meteosensitivity the increased frequency of registering of complaints and clinical manifestations of АН and electrocardiographic signs suggesting worsening of the dysfunction of the cardiovascular system were re-vealed. It has been shown that the increased pathological meteosensitivity of an or-ganism is associated with the changes in lipid and carbonate metabolism, important in the development of АН. Pathological meteosensitivity of an organism should be considered as another important risk factor for progression of AH in extreme meteorological and geophysical conditions of the North.

meteosensitivity, arterial hypertension, North.

1. Katyukhin, V. N. Arterial'naya gipertenziya na Severe / V. N. Katyukhin, D. V. Bazhukhin, I. F. Bazhukhina. – Surgut : SUR-GU, 2000. – 132 s.
2. Hasnulin, V. I. Northern cardiometeopathies / V. I. Hasnulin, A. V. Hasnulina, E. V. Sevostyanova. – Novosibirsk: Creative Union «South-West», 2004. – 220 p.
3. Epidemiologiya, patogenez, profilaktika i lecheniye arterial'noy gipertenzii u prishlogo naseleniya na Severe / YU.A. Nikolayev, S. A. Daryanina, A. I. Pal'tsev [i dr.]. – Novosibirsk : SO RAMN, 2005. – 200 s.
4. Zapesochnaya, I. L. Osobennosti techeniya arterial'noy gipertonii v severnykh regionakh strany / I.L.Zapesochnaya, A. G. Avtandilov // Klinicheskaya meditsina. 2008. – T. 86, № 5. – S. 42–44.
5. Khamnagadayev, I. I. Rasprostranennost' arterial'noy gipertenzii, ishemi-cheskoy bolezni serdtsa i ikh faktorov riska sredi sel'skogo korennogo i prishlogo naseleniya Severa i Tsentral'noy Sibiri : avtoref. dis. … d-ra med. nauk / Khamnagadayev I. I. – Tomsk, 2008. – 49 s.
6. Khasnulin, V. I. Arterial'naya gipertenziya na Severe / V. I. Khasnulin, P. V. Khasnulin // Problemy zdravookhraneniya i sotsial'nogo razvitiya Arkticheskoy zony Rossii. – M. : Paulsen, 2011. – S. 241–253.
7. Polikarpov, L. S. Meteotropnyye reaktsii serdechno-sosudistoy sistemy i ikh profilaktika / L. S. Polikarpov, A.V.Lapko, I. I. Khamnagadayev. – Novosibirsk : Nauka, 2005. – 196 s.
8. Näyhä, S. Cold and the risk of cardiovascular diseases. A review / S. Näyhä // Int. J. Circumpolar Health. – 2002. – Vol. 61, № 4. – P. 373–380.
9. Gyllerup, S. Cold climate and coronary mortality in Sweden / S. Gyllerup // Int. J. Circumpolar Health. – 2000. – Vol. 59, № 3–4. – P. 160–163.
10. Zhdanova, F. G. Kharakteristika narusheniy ritma serdtsa u muzhskogo naseleniya Zapolyar'ya : avtoref. dis. …kand. med. nauk / Zhdanova F. G. – M., 1989. – 21 s.
11. Khasnulin, V. I. Vvedeniye v polyarnuyu meditsinu / V. I. Khasnulin. – Novosi-birsk : SO RAMN, 1998. – 337 s.
12. Davidenko, V. I. Funktsional'nyy rezerv serdechno-sosudistoy sistemy pri adaptatsii i patologii cheloveka na Kraynem Severe i v Antarktide : avtoref. dis. … d-ra med. nauk / Davidenko V. I. – Novosibirsk, 1996. – 67 s.
13. Panin, L. Ye. Gomeostaz i problemy pripolyarnoy meditsiny (metodologicheskiye aspekty adaptatsii) / L.Ye.Panin // Byulleten' SO RAMN. – 2010. – T. 30, № 3 . – S. 6–11.
14. Boyko, Ye. R. Nekotoryye zakonomernosti metabolicheskikh perestroyek u cheloveka na Kraynem Severe / Ye. R. Boyko // Fiziologiya cheloveka. – 1996. – № 4. – C. 122–129.